Fioricet is a prescription medication that relieves tension headaches. It contains acetaminophen, a pain treatment; butalbital, a barbiturate that calms muscle spasms; and caffeine, which increases the effects of acetaminophen. This combination successfully relieves headache symptoms like pain, tension, and discomfort. Fioricet is frequently prescribed when other pain relievers are unsuccessful. It relieves headaches by relaxing muscular tension, increasing blood flow, and lowering their severity.